E466A : Mutation rate in yeast

The Saccharomyces cerevisiae pol3-E471A mutation mimicking human POLD1-E466A did not affect the mutation rate.

• Prindle, M.J. A substitution in the fingers domain of DNA polymerase δ reduces fidelity by altering nucleotide discrimination in the catalytic site. J Biol Chem 288, 5572-5580 (2013). https://pubmed.ncbi.nlm.nih.gov/23283971/