About PolED
The PolED database compiles information on functional studies of POLE and POLD1 variants reported in humans. It is primarily intended for clinicians and researchers who use POLE and POLD1 status to stratify patients.
Contribute to the database
If you have a new publication describing functional studies of POLE or POLD1 variants or notice any omissions in this database, please use the "Submit Data" button in the navigation bar to communicate this information.
Last update: Aug 24, 2026 18:40 UTC: redesign, variant browser search bar