N336S : Mutation rate in yeast
The Saccharomyces cerevisiae pol2-N351S mutation mimicking human POLE-N336S does not affect the mutation rate.
References
- Barbari, S.R., Kane, D.P., Moore, E.A. & Shcherbakova, P.V. Functional analysis of cancer-associated DNA polymerase ε variants in Saccharomyces cerevisiae. G3 (Bethesda) 8, 1019-1029 (2018). https://pubmed.ncbi.nlm.nih.gov/29352080/